Articles with "dapsone" as a keyword



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Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.18888

Abstract: 1. Liu H, Wang Z, Bao F, et al; and the Dapsone Hypersensitivity Syndrome Prevention Working Group. Evaluation of prospective HLA-B*13:01 screening to prevent dapsone hypersensitivity syndrome in patients with leprosy. JAMA Dermatol. 2019;155(6):666-672. doi:10.1001/jamadermatol.2018.5360… read more here.

Keywords: dapsone hypersensitivity; dapsone; hypersensitivity syndrome; author affiliations ... See more keywords
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Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature

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Published in 2019 at "European Journal of Pediatrics"

DOI: 10.1007/s00431-019-03409-5

Abstract: Immunoglobulin A (IgA) vasculitis (Henoch-Schonlein purpura (HSP)) is the most common vasculitis in children. It is characterized by purpuric rash, arthritis, gastrointestinal, and/or renal involvement. Spontaneous resolution is the typical outcome. In chronic cutaneous manifestations… read more here.

Keywords: vasculitis henoch; vasculitis; treatment; iga vasculitis ... See more keywords
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Emerging Technologies to Target Drug Delivery to the Skin - the Role of Crystals and Carrier-Based Systems in the Case Study of Dapsone.

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Published in 2020 at "Pharmaceutical research"

DOI: 10.1007/s11095-020-02951-4

Abstract: Dapsone (DAP) is a long-established molecule that remains a promising therapeutic agent for various diseases mainly because it combines antimicrobial and anti-inflammatory activities. Its oral application, however, is limited by the dose-dependent hematological side effects… read more here.

Keywords: emerging technologies; delivery; technologies target; drug ... See more keywords
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Dapsone in Hidradenitis Suppurativa: A Systematic Review

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Published in 2022 at "Dermatology and Therapy"

DOI: 10.1007/s13555-021-00674-x

Abstract: Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent disease, usually presenting after puberty with inflammatory lesions that mainly affect the apocrine gland-bearing areas of the body, most commonly the axillary, inguinal and anogenital regions. The… read more here.

Keywords: dapsone; treatment; systematic review; hidradenitis suppurativa ... See more keywords
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Severe dapsone-induced hypoalbuminemia in a case of mucous membrane pemphigoid

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Published in 2020 at "JAAD Case Reports"

DOI: 10.1016/j.jdcr.2020.08.018

Abstract: INTRODUCTION Dapsone, or 4,49-diaminodiphenylsulfone, is commonly used in several dermatologic indications such as neutrophilic dermatoses, vasculitis, and autoimmune bullous diseases. Historically, dapsone was used for sleep disorders and then as an antibiotic to treat streptococcal… read more here.

Keywords: dapsone induced; severe dapsone; dapsone; case ... See more keywords
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Dapsone reduced acetic acid-induced inflammatory response in rat colon tissue through inhibition of NF-kB signaling pathway

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Published in 2019 at "Immunopharmacology and Immunotoxicology"

DOI: 10.1080/08923973.2019.1678635

Abstract: Abstract Aim: The purpose of this study is to examine the protective effects of Dapsone on inflammation of intestinal tissue through inhibition of NF-kB pathway in acetic acid-induced colitis in rats. Methods: Acute colitis was… read more here.

Keywords: acid induced; inhibition; tissue; acetic acid ... See more keywords
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D-optimal mixture design for optimization of topical dapsone niosomes: in vitro characterization and in vivo activity against Cutibacterium acnes

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Published in 2022 at "Drug Delivery"

DOI: 10.1080/10717544.2022.2048131

Abstract: Abstract This study aimed to illustrate the use of D-optimal mixture design (DOMD) for optimization of an enhancer containing Dapsone niosomal formula for acne topical treatment. Mixture components (MixCs) studied were: Span 20, Cholesterol, and… read more here.

Keywords: optimal mixture; vivo; mixture; dapsone ... See more keywords
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Dapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria

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Published in 2022 at "Hematology"

DOI: 10.1080/16078454.2022.2149943

Abstract: ABSTRACT Background The appearance of bite cells associated with methemoglobinemia can be caused by oxidizing drugs such as dapsone in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or high drug serum levels. Bite cells are often… read more here.

Keywords: hemolysis; dapsone; g6pd deficiency; idiopathic urticaria ... See more keywords
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882: Use of Cimetidine to Reduce Dapsone-Induced Toxicity in a Non-G6PD-Deficient Transplant Recipient

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Published in 2020 at "Critical Care Medicine"

DOI: 10.1097/01.ccm.0000729416.23584.ed

Abstract: INTRODUCTION: Dapsone is a commonly used alternative for the prevention of Pneumocystis jirovecii pneumonia (PJP) in immunocompromised patients However, its use is limited by its significant dose-dependent hematologic adverse effects such as dapsone-induced methemoglobinemia by… read more here.

Keywords: dapsone induced; transplant; cimetidine; toxicity ... See more keywords
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Cholesterol-dependent activity of dapsone against non-replicating persistent mycobacteria.

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Published in 2022 at "Microbiology"

DOI: 10.1099/mic.0.001279

Abstract: One-third of the world's population is estimated to be latently infected with Mycobacterium tuberculosis. This reservoir of bacteria is largely resistant to antimicrobial treatment that often only targets actively replicating mycobacteria, with current treatment for… read more here.

Keywords: non replicating; dapsone; activity; cholesterol dependent ... See more keywords
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Topical dapsone gel is a new treatment option for acne agminata

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Published in 2019 at "Clinical and Experimental Dermatology"

DOI: 10.1111/ced.13742

Abstract: Acne agminata (AA) is a rare centrofacial papular eruption of unknown aetiology. There are very few reports of effective treatment options for AA. We report a case with minimal response to conventional treatments, including oral… read more here.

Keywords: acne agminata; topical dapsone; treatment; dapsone ... See more keywords