Cost‐effectiveness analysis of 30‐month vs 12‐month dual antiplatelet therapy with clopidogrel and aspirin after drug‐eluting stents in patients with acute coronary syndrome
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DOI: 10.1002/clc.22756
Abstract: Continuation of dual antiplatelet therapy (DAPT) beyond 1 year reduces late stent thrombosis and ischemic events after drug‐eluting stents (DES) but increases risk of bleeding. We hypothesized that extending DAPT from 12 months to 30… read more here.
Keywords: dapt; antiplatelet; continuation; dapt continuation ... See more keywords
Should PRECISE-DAPT be included for long-term prognostic stratification of diabetic patients with NSTEACS?
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DOI: 10.1007/s00592-021-01792-w
Abstract: There are insufficient data regarding risk scores validation in patients with diabetes mellitus and non-ST elevation acute coronary syndrome (NSTEACS). We performed a diabetes mellitus-specific analysis of cardiovascular outcomes after NSTEACS. We tested the predictive… read more here.
Keywords: dapt; predictive power; precise dapt; diabetic patients ... See more keywords
Dual antiplatelet therapy in the contemporary drug-eluting stents era: from vulnerable stents to vulnerable patients
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DOI: 10.1007/s11239-022-02639-z
Abstract: In this issue of the Journal of Thrombosis and Thrombolysis, Dr. Chong and colleagues present a Bayesian network meta-analysis of 15 randomized controlled trials (RCTs) and 43,875 patients in which different DAPT durations, e.g. short… read more here.
Keywords: dual antiplatelet; drug; polymer; antiplatelet therapy ... See more keywords
Rationale and design of the EVOLVE Short DAPT Study to assess 3‐month dual antiplatelet therapy in subjects at high risk for bleeding undergoing percutaneous coronary intervention
Sign Up to like & getrecommendations! Published in 2018 at "American Heart Journal"
DOI: 10.1016/j.ahj.2018.08.004
Abstract: Background While extended dual antiplatelet therapy (DAPT) with aspirin and a platelet (P2Y12) inhibitor after percutaneous coronary intervention (PCI) reduces the risk of stent thrombosis (ST) and myocardial infarction (MI), it also increases bleeding. Newer… read more here.
Keywords: dapt; risk; evolve short; dapt study ... See more keywords
Design and Rationale of the XIENCE Short DAPT Clinical Program: an Assessment of the Safety of 3-month or 1-month DAPT in Patients at High Bleeding Risk Undergoing PCI with an Everolimus-Eluting Stent.
Sign Up to like & getrecommendations! Published in 2020 at "American heart journal"
DOI: 10.1016/j.ahj.2020.09.019
Abstract: Dual antiplatelet therapy (DAPT) is key for the prevention of recurrent ischemic events after percutaneous coronary intervention (PCI), however, it increases the risk of bleeding complications. While new generation drug-eluting stents have been shown superior… read more here.
Keywords: dapt; program; xience short; xience ... See more keywords
Dual versus single antiplatelet therapy after coronary artery bypass graft surgery: An updated meta-analysis.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.07.083
Abstract: INTRODUCTION The potential benefit and risks of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients who undergo coronary artery bypass graft surgery (CABG) is controversial. METHODS We performed a systematic review and… read more here.
Keywords: dapt; graft; antiplatelet therapy; single antiplatelet ... See more keywords
The effect of post-operative antithrombotic therapy on lower extremity outcomes following infrapopliteal bypass for chronic limb-threatening ischemia.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of vascular surgery"
DOI: 10.1016/j.jvs.2022.01.011
Abstract: OBJECTIVE While current guidelines recommend single antiplatelet therapy (SAPT) for patients undergoing revascularization for chronic limb-threatening ischemia (CLTI), antithrombotic management varies by patient and provider. Our aim was to examine the impact of different post-operative… read more here.
Keywords: infrapopliteal bypass; therapy; year; bypass ... See more keywords
The Notch signaling pathway inhibitor Dapt alleviates autism-like behavior, autophagy and dendritic spine density abnormalities in a valproic acid-induced animal model of autism
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DOI: 10.1016/j.pnpbp.2019.109644
Abstract: Autism spectrum disorders (ASDs) comprise a number of heterogeneous neurodevelopmental diseases. Recent studies suggest that the abnormal transmission of neural signaling pathways is associated with the pathogenesis of autism. The aim of this study was… read more here.
Keywords: dapt; autism; signaling pathway; model ... See more keywords
Tailoring duration of DAPT with risk scores
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DOI: 10.1016/s0140-6736(17)30591-3
Abstract: www.thelancet.com Vol 389 March 11, 2017 987 Dual antiplatelet therapy (DAPT) reduces stent thrombosis and ischaemic events after percutaneous coronary intervention (PCI), but increases the risk of bleeding. Current guidelines recommend default DAPT durations of… read more here.
Keywords: dapt; risk; high bleeding; duration dapt ... See more keywords
Drug-eluting stents in elderly patients with coronary artery disease (SENIOR): a randomised single-blind trial
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DOI: 10.1016/s0140-6736(17)32713-7
Abstract: BACKGROUND Elderly patients regularly receive bare-metal stents (BMS) instead of drug-eluting stents (DES) to shorten the duration of double antiplatelet therapy (DAPT). The aim of this study was to compare outcomes between these two types… read more here.
Keywords: dapt; duration; group; coronary artery ... See more keywords
ABBREVIATED DAPT FOLLOWED BY P2Y12 MONOTHERAPY AS COMPARED TO STANDARD DAPT POST-PCI: A SYSTEMATIC REVIEW AND META-ANALYSIS
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DOI: 10.1016/s0735-1097(20)30698-7
Abstract: At least 12 months of dual antiplatelet therapy [DAPT] after percutaneous coronary intervention [PCI] was recommended following reports of increased stent thrombosis in patients treated with first generation drug eluting stents [DES]. However in the… read more here.
Keywords: dapt; dapt followed; abbreviated dapt; p2y12 monotherapy ... See more keywords