Articles with "dapt ly294002" as a keyword



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Notch1 and PI3K/Akt signaling blockers DAPT and LY294002 coordinately inhibit metastasis of gastric cancer through mutual enhancement

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Published in 2019 at "Cancer Chemotherapy and Pharmacology"

DOI: 10.1007/s00280-019-03990-4

Abstract: Purpose Blockade of either Notch1 or PI3K/Akt pathway inhibits metastasis of gastric cancer. However, whether blockade of both pathways coordinately exerts such an effect remains unknown. In this study, we aimed to investigate the effects… read more here.

Keywords: dapt ly294002; gastric cancer; pi3k akt; metastasis gastric ... See more keywords