Primary human monocytes differentiate into M2 macrophages and involve Notch-1 pathway.
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DOI: 10.1139/cjpp-2016-0319
Abstract: The current study investigates whether inhibiting the Notch-1 signaling pathway in primary human monocytes enhances M2 macrophage differentiation. We generated a primary human monocyte cell culture model to understand the effect of the Notch-1 signaling… read more here.
Keywords: dapt sirna; human monocytes; inflammatory cytokines; notch pathway ... See more keywords