Growth Arrest of Staphylococcus aureus Induces Daptomycin Tolerance via Cell Wall Remodelling
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DOI: 10.1128/mbio.03558-22
Abstract: Understanding why antibiotics sometimes fail to cure infections is fundamental to improving treatment outcomes. This is a major challenge when it comes to Staphylococcus aureus because this pathogen causes several different chronic or recurrent infections.… read more here.
Keywords: wall; daptomycin tolerance; growth; staphylococcus aureus ... See more keywords
Proteome profiling of evolved methicillin-resistant Staphylococcus aureus strains with distinct daptomycin tolerance and resistance phenotypes
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DOI: 10.3389/fmicb.2022.970146
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is a highly dangerous pathogen, and daptomycin has been increasingly used to treat its infections in clinics. Recently, several groups have shown that tolerance and resistance of microbes can evolve rapidly… read more here.
Keywords: daptomycin tolerance; tolerance resistance; methicillin resistant; resistance ... See more keywords