Accurate determination of drug-to-antibody ratio of interchain cysteine-linked antibody–drug conjugates by LC-HRMS
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02280-5
Abstract: Accurate determination of the drug-to-antibody ratio (DAR) of interchain cysteine-linked antibody–drug conjugates (ADCs) is challenging. High-resolution mass spectrometry (HRMS) analysis of the ADCs at the intact or subunit level provides a feasible way to measure… read more here.
Keywords: dar; cysteine linked; accurate determination; drug ... See more keywords
Interobserver and intraobserver reliability of determining the deformity angular ratio in severe pediatric deformity curves.
Sign Up to like & getrecommendations! Published in 2020 at "Spine deformity"
DOI: 10.1007/s43390-020-00239-6
Abstract: STUDY DESIGN Cross-sectional reliability study. OBJECTIVE The deformity angular ratio (DAR) is a means of quantifying magnitude of the coronal (C-DAR) and sagittal (S-DAR) plane of deformity curves to produce a total DAR (T-DAR). It… read more here.
Keywords: dar dar; range; dar; deformity angular ... See more keywords
DAR-901 vaccine for the prevention of infection with Mycobacterium tuberculosis among BCG-immunized adolescents in Tanzania: A randomized controlled, double-blind phase 2b trial.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.09.055
Abstract: BACKGROUND SRL172 prevented disease due to Mycobacterium tuberculosis in a Phase 3 trial. DAR-901 represents a scalable manufacturing process for SRL172. We sought to determine if DAR-901 would prevent infection with M. tuberculosis among BCG-primed… read more here.
Keywords: dar 901; trial; dar; infection ... See more keywords
Results from TRIO030, a pre-surgical tissue-acquisition study to evaluate molecular alterations in human breast cancer tissue following short-term exposure to the androgen receptor antagonist darolutamide
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz239.076
Abstract: Abstract Background The role of the androgen receptor (AR) in breast cancer (BC) is not fully elucidated. TRIO030 was conducted to identify molecular changes in BC tissue following short-term exposure to darolutamide (DAR), a new… read more here.
Keywords: dar; exposure; tissue; androgen receptor ... See more keywords
Learning from Ambiguous Labels for Lung Nodule Malignancy Prediction
Sign Up to like & getrecommendations! Published in 2022 at "IEEE transactions on medical imaging"
DOI: 10.1109/tmi.2022.3149344
Abstract: Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since… read more here.
Keywords: nodule malignancy; malignancy prediction; set set; prediction ... See more keywords
Different Degrees of 5'-to-3' DAR Interactions Modulate Zika Virus Genome Cyclization and Host-Specific Replication
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Virology"
DOI: 10.1128/jvi.01602-19
Abstract: Flaviviruses naturally cycle between the mosquito vector and vertebrate hosts. The disparate hosts provide selective pressures that drive virus genome evolution to maintain efficient replication during host alteration. Host adaptation may occur at different stages… read more here.
Keywords: replication; mosquito; host specific; genome cyclization ... See more keywords
Development of an Allogeneic Anti-Bcma T Cell Therapy Utilizing a Novel Dimeric Antigen Receptor (DAR) Structure
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-131892
Abstract: Background: Multiple myeloma remains an incurable malignancy of plasma cells. Adoptive transfer of chimeric antigen receptor (CAR)-expressing T cells is a promising new therapy for hematologic malignancies. B-cell maturation antigen (BCMA) is a protein that… read more here.
Keywords: anti bcma; equity ownership; dar;
Urinary schistosomiasis among preschool-age children in an endemic area of Kinondoni municipality, Dar es Salaam, Tanzania 2016
Sign Up to like & getrecommendations! Published in 2017 at "Asian Pacific Journal of Tropical Disease"
DOI: 10.12980/apjtd.7.2017d6-359
Abstract: *Corresponding author: Donath Samuel Tarimo, United Nations Road, P.O.Box 65015, Dar es Salaam, United Republic of Tanzania. Tels: +255 754 820 439 (BS Ng`weng`weta); +255 754 578 528 (TD Samuel) E-mails: [email protected] (BS Ng`weng`weta); [email protected]… read more here.
Keywords: dar salaam; dar; tanzania; urinary schistosomiasis ... See more keywords
Effect of Dietary Amylose/Amylopectin Ratio on Intestinal Health and Cecal Microbes’ Profiles of Weaned Pigs Undergoing Feed Transition or Challenged With Escherichia coli Lipopolysaccharide
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.693839
Abstract: Background Dietary amylose/amylopectin ratio (DAR) plays an important role in piglets’ intestinal health. It is controversial whether diarrhea could be relieved by changing DAR in weaning piglets. Methods Sixty (Landrace × Yorkshire) castrated male pigs… read more here.
Keywords: dar; feed transition; amylose amylopectin; group ... See more keywords
Comprehensive In Silico Characterization and Expression Pro-Filing of DA1/DAR Family Genes in Brassica rapa
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091577
Abstract: The DA1/DAR family genes have been shown to play important roles in regulating organ size and plant biomass in the model plant Arabidopsis and several crops. However, this family has not been characterized in Brassica… read more here.
Keywords: dar; brassica rapa; family genes; dar family ... See more keywords
Anadolu Selçuklu Medreseleri ve Darüşşifalarında Türbe
Sign Up to like & getrecommendations! Published in 2019 at "Belleten"
DOI: 10.37879/belleten.2019.519
Abstract: Anadolu Selçuklu döneminde kentlerin tarihi dokusu içindeki en anıtsal yapıları medreseler ve darüşşifalar oluşturmaktadır. Bu dönemde medreseler ve darüşşifaların içinde ya da bitişiğinde mescit ve türbe gibi farklı işlevli birimler yer alır. Bu bağlamda medrese… read more here.
Keywords: sel uklu; rbe; dar; dar ifalar ... See more keywords