DAR-901 vaccine for the prevention of infection with Mycobacterium tuberculosis among BCG-immunized adolescents in Tanzania: A randomized controlled, double-blind phase 2b trial.
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DOI: 10.1016/j.vaccine.2020.09.055
Abstract: BACKGROUND SRL172 prevented disease due to Mycobacterium tuberculosis in a Phase 3 trial. DAR-901 represents a scalable manufacturing process for SRL172. We sought to determine if DAR-901 would prevent infection with M. tuberculosis among BCG-primed… read more here.
Keywords: dar 901; trial; dar; infection ... See more keywords
CD4+ T cell cytokine responses to the DAR-901 booster vaccine in BCG-primed adults: A randomized, placebo-controlled trial
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DOI: 10.1371/journal.pone.0217091
Abstract: Background DAR-901 is an inactivated whole cell tuberculosis booster vaccine, prepared using a new scalable, broth-grown method from the master cell bank of SRL172, a vaccine previously shown to prevent tuberculosis. This study examined whether… read more here.
Keywords: dar 901; cytokine; vaccine; cd4 cell ... See more keywords