Deciphering the Dark Proteome: Use of the Testis and Characterization of Two Dark Proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.8b00387
Abstract: For the C-HPP consortium, dark proteins include not only uPE1, but also missing proteins (MPs, PE2-4), smORFs, proteins from lncRNAs, and products from uncharacterized transcripts. Here, we investigated the expression of dark proteins in the… read more here.
Keywords: expressed testis; testis; dark proteome; dark proteins ... See more keywords
Analysis of the dark proteome of Chandipura virus reveals maximum propensity for intrinsic disorder in phosphoprotein
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DOI: 10.1038/s41598-021-92581-6
Abstract: Chandipura virus (CHPV, a member of the Rhabdoviridae family) is an emerging pathogen that causes rapidly progressing influenza-like illness and acute encephalitis often leading to coma and death of the human host. Given several CHPV… read more here.
Keywords: analysis; disorder; chandipura virus; dark proteome ... See more keywords
On the Helix Propensity in Generalized Born Solvent Descriptions of Modeling the Dark Proteome
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2017.00003
Abstract: Intrinsically disordered proteins that populate the so-called “Dark Proteome” offer challenging benchmarks of atomistic simulation methods to accurately model conformational transitions on a multidimensional energy landscape. This work explores the application of parallel tempering with… read more here.
Keywords: generalized born; born solvent; propensity generalized; dark proteome ... See more keywords