Through a glass, darkly? HepaRG and HepG2 cells as models of human Phase I drug metabolism.
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DOI: 10.1080/03602532.2022.2039688
Abstract: The pharmacokinetic and safety assessment of drug candidates is becoming increasingly dependent upon in vitro models of hepatic metabolism and toxicity. Predominant among these is the HepG2 cell line, although HepaRG is becoming increasingly popular… read more here.
Keywords: drug; glass darkly; darkly heparg; metabolism ... See more keywords