The expression of tyrosine hydroxylase and DARPP‐32 in the house crow (Corvus splendens) brain
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24649
Abstract: Birds of the family Corvidae which includes diverse species such as crows, rooks, ravens, magpies, jays, and jackdaws are known for their amazing abilities at problem‐solving. Since the catecholaminergic system, especially the neurotransmitter dopamine, plays… read more here.
Keywords: corvus splendens; house; darpp; tyrosine hydroxylase ... See more keywords
DARPP‐32 distinguishes a subset of adult‐born neurons in zebra finch HVC
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25245
Abstract: Adult male zebra finches (Taeniopygia guttata) continually incorporate adult‐born neurons into HVC, a telencephalic brain region necessary for the production of learned song. These neurons express activity‐dependent immediate early genes (e.g., zenk and c‐fos) following… read more here.
Keywords: darpp; hvc; hvc nns; adult ... See more keywords
DARPP‐32 cells and neuropil define striosomal system and isolated matrix cells in human striatum
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25473
Abstract: The dorsal striatum forms a central node of the basal ganglia interconnecting the neocortex and thalamus with circuits modulating mood and movement. Striatal projection neurons (SPNs) include relatively intermixed populations expressing D1‐type or D2‐type dopamine… read more here.
Keywords: matrix; striatum; human striatum; darpp ... See more keywords
DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
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DOI: 10.1038/s42003-018-0050-6
Abstract: Lung cancer is the leading cause of cancer-related death worldwide. Here we demonstrate that elevated expression of dopamine and cyclic adenosine monophosphate-regulated phosphoprotein, Mr 32000 (DARPP-32), and its truncated splice variant t-DARPP promote lung tumor… read more here.
Keywords: cell; darpp; lung cancer; growth ... See more keywords
t-Darpp Activates IGF-1R Signaling to Regulate Glucose Metabolism in Trastuzumab-Resistant Breast Cancer Cells
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DOI: 10.1158/1078-0432.ccr-17-0824
Abstract: Purpose: Increased glycolysis and glucose dependence is a hallmark of malignancy that enables tumors to maximize cell proliferation. In HER2+ cancers, an increase in glycolytic capacity is associated with trastuzumab resistance. IGF-1R activation and t-Darpp… read more here.
Keywords: breast; igf signaling; darpp; glucose metabolism ... See more keywords
Abstract 356: DARPP-32, a bridge between pro-inflammatory NF-kB and STAT3 signaling in gastric cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-356
Abstract: Background: Gastric cancer is one of the most frequently diagnosed malignancies with poor prognosis in the world. We have previously shown that Dopamine and cAMP-regulated phosphoprotein, Mr 32000 (DARPP-32) is a novel cancer gene, which… read more here.
Keywords: gastric cancer; darpp; cancer; pro inflammatory ... See more keywords