DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m6A modification and translation for cytoprotective autophagy in cervical cancer
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2079889
Abstract: ABSTRACT Cervical cancer (CC) is one of the most prevalent malignancies among females. Cytoprotective autophagy could confer cancer cell tolerance to hypoxic stress, promoting cell survival and adaptation. Aspartyl-tRNA synthetase 1 antisense 1 (DARS-AS1) is… read more here.
Keywords: dars as1; cytoprotective autophagy; cervical cancer; dars mrna ... See more keywords
LncRNA DARS-AS1 aggravates the growth and metastasis of hepatocellular carcinoma via regulating the miR-3200-5p-Cytoskeleton associated protein 2 (CKAP2) axis.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1982272
Abstract: Accumulating signs have found that long noncoding RNAs (lncRNAs) contribute to hepatocellular carcinoma (HCC). Here, we probed the effect and mechanism of lncRNA DARS-AS1 in HCC. The profiles of DARS-AS1 and Cytoskeleton associated protein 2… read more here.
Keywords: hepatocellular carcinoma; hcc; lncrna dars; dars as1 ... See more keywords
Novel lnc RNA regulated by HIF‐1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia
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DOI: 10.14814/phy2.13203
Abstract: Chronic tubulointerstitial hypoxia plays an important role as the final common pathway to end‐stage renal disease. HIF‐1 (hypoxia‐inducible factor‐1) is a master transcriptional factor under hypoxia, regulating downstream target genes. Genome‐wide analysis of HIF‐1 binding… read more here.
Keywords: hif; dars as1; apoptotic cell; cell death ... See more keywords
LncRNA DARS-AS1 regulates microRNA-129 to promote malignant progression of thyroid cancer.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201912_19683
Abstract: OBJECTIVE To investigate the expression of long non-coding RNA (lncRNA) DARS-AS1 in thyroid cancer, and to further investigate whether it can promote the development of thyroid cancer by regulating microRNA-129. PATIENTS AND METHODS Real-time quantitative… read more here.
Keywords: microrna 129; expression; dars as1; thyroid cancer ... See more keywords