Impact of Host Flexibility on Selectivity in a Supramolecular Host-Catalyzed Enantioselective aza-Darzens Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c04182
Abstract: A highly enantioselective aza-Darzens reaction (up to 99% ee) catalyzed by an enantiopure supramolecular host has been discovered. To understand the role of host structure on reaction outcome, nine new gallium(III)-based enantiopure supramolecular assemblies were… read more here.
Keywords: enantioselective aza; supramolecular host; aza darzens; darzens reaction ... See more keywords
Catalytic Asymmetric Intramolecular Darzens Reaction of 2-Halomalonate Derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Communications"
DOI: 10.1177/1934578x19884409
Abstract: A catalytic asymmetric intramolecular Darzens reaction of 2-halomalonate derivatives was developed for the enantioselective preparation of chiral building blocks for epoxide-containing natural products. Among the screened catalysts, some phase-transfer catalysts gave the desired epoxide in… read more here.
Keywords: catalytic asymmetric; reaction halomalonate; halomalonate derivatives; intramolecular darzens ... See more keywords