Dasatinib-induced chylothorax: report of a case and review of the literature
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DOI: 10.1007/s10637-020-00932-3
Abstract: Dasatinib is a tyrosine kinase inhibitor for the treatment of BCR-ABL-positive chronic myeloid leukaemia (CML) or Philadelphia chromosome-positive acute lymphoblastic leukaemia (ALL). Although fluid retention is a common adverse event associated with dasatinib, chylothorax is… read more here.
Keywords: dasatinib induced; chylothorax; dasatinib; case ... See more keywords
Dasatinib-induced colitis: clinical, endoscopic and histological findings
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DOI: 10.1080/00365521.2021.2022190
Abstract: Abstract Background Dasatinib, a second-generation tyrosine kinase inhibitor, is widely used in patients with haematological malignancies. The main side effects of dasatinib are myelosuppression and pleural effusion; however, colitis, such as haemorrhagic colitis and cytomegalovirus… read more here.
Keywords: dasatinib induced; colitis; clinical endoscopic; induced colitis ... See more keywords
Dasatinib-induced Crohn’s-like colitis
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DOI: 10.1136/jclinpath-2022-208340
Abstract: Dasatinib is a second-generation multityrosine kinase inhibitor used in the first-line and second-line treatment of Philadelphia chromosome-positive leukaemia. The most frequent type of Dasatinib-induced intestinal injury is haemorrhagic colitis; other morphologic patterns include apoptotic colopathy,… read more here.
Keywords: dasatinib induced; crohn like; colitis; treatment ... See more keywords
Dasatinib-induced pulmonary arterial hypertension – A rare late complication
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155217753740
Abstract: Dasatinib is a dual Src/Abl tyrosine kinase inhibitor approved for frontline and second line treatment of chronic phase chronic myelogenous leukemia. Pulmonary arterial hypertension is defined by an increase in mean pulmonary arterial pressure >25 mmHg… read more here.
Keywords: dasatinib induced; arterial hypertension; induced pulmonary; pulmonary arterial ... See more keywords
Dasatinib-induced spleen contraction leads to transient lymphocytosis.
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DOI: 10.1182/bloodadvances.2022009279
Abstract: Key Points • By promoting stromal cell contractility, dasatinib leads to a transient egress of lymphocytes from the spleen.• Dasatinib-induced spleen resizing and lymphocyte mobilization open new possibilities for clinical applications. read more here.
Keywords: dasatinib induced; induced spleen; contraction leads; leads transient ... See more keywords
Dasatinib-induced Nonspecific Interstitial Pneumonia That Developed 7 Years after the Initiation of Dasatinib
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DOI: 10.2169/internalmedicine.4714-20
Abstract: We report the case of a 56-year-old man with chronic myeloid leukemia (CML) who developed dasatinib-induced interstitial lung disease (ILD) 7 years after starting dasatinib, a BCR-ABL1 inhibitor. The patient presented with dyspnea. Chest imaging… read more here.
Keywords: dasatinib induced; induced nonspecific; dasatinib; interstitial pneumonia ... See more keywords
Relationship between Dasatinib-induced Pulmonary Hypertension and Drug Dose
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DOI: 10.2169/internalmedicine.8392-21
Abstract: Objective Dasatinib, a second-generation tyrosine kinase inhibitor, is used for chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It reportedly causes pulmonary arterial hypertension (PAH) and the dose-dependent induction of apoptosis… read more here.
Keywords: dasatinib induced; hypertension; relationship dasatinib; drug dose ... See more keywords
Dasatinib-induced Pulmonary Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Internal Medicine"
DOI: 10.2169/internalmedicine.9107-21
Abstract: In recent years, cardio-oncology has become a field of interest. Cancer drug therapies and radiation therapy are sometimes associated with various cardiovascular complications, such as myocardial damage, myocarditis, pericarditis, coronary artery disease, arrhythmia, hypertension, and… read more here.
Keywords: dasatinib induced; pulmonary hypertension; incidence; induced pulmonary ... See more keywords