Articles with "dat" as a keyword



Comment on: Dopamine Transporter (DaT) Scan Utilization in a Movement Disorder Center

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Published in 2017 at "Movement Disorders Clinical Practice"

DOI: 10.1002/mdc3.12369

Abstract: In response to the interesting article by Oravivattanakul et al. in Movement Disorders Clinical Practice, I would like to say that in the majority of centers in the UK, the method of estimation of radiotracer… read more here.

Keywords: movement; transporter dat; dat scan; dat ... See more keywords
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Effects of animal handling on striatal DAT availability in rats

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Published in 2020 at "Annals of Nuclear Medicine"

DOI: 10.1007/s12149-020-01476-5

Abstract: Objective Positron emission tomography (PET) is a non-invasive technique measuring quantification of physiological and biochemical processes in the living organism. However, there are many considerations including anesthesia and fasting to acquire small animal imaging. We… read more here.

Keywords: animal handling; group; kept anesthesia; effects animal ... See more keywords
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The Application of Decellularized Adipose Tissue Promotes Wound Healing.

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Published in 2020 at "Tissue engineering and regenerative medicine"

DOI: 10.1007/s13770-020-00286-0

Abstract: BACKGROUND Due to adipose-derived stem cells (ASCs) being easy to obtain, their rapid proliferation rate, and their multidirectional differentiation capabilities, they have been widely used in the field of regenerative medicine. With the progress of… read more here.

Keywords: medicine; decellularized adipose; tissue; adipose tissue ... See more keywords

Demonstrating Bioequivalence for Two Dose Strengths of Niraparib and Abiraterone Acetate Dual-Action Tablets Versus Single Agents: Utility of Clinical Study Data Supplemented with Modeling and Simulation

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Published in 2024 at "Clinical Pharmacokinetics"

DOI: 10.1007/s40262-023-01340-5

Abstract: The combination of niraparib and abiraterone acetate (AA) plus prednisone is under investigation for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC). Regular-strength (RS) and lower-strength (LS)… read more here.

Keywords: niraparib abiraterone; sac; dat; study ... See more keywords

Dopamine and norepinephrine transporter inhibition for long-term fear memory enhancement

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Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2019.112266

Abstract: Psychostimulants are highly effective cognitive-enhancing therapeutics yet have a significant potential for abuse and addiction. While psychostimulants likely exert their rewarding and addictive properties through dopamine transporter (DAT) inhibition, the mechanisms of their procognitive effects… read more here.

Keywords: long term; inhibition; fear memory; dat ... See more keywords
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Dopamine transporter gene expression within the nucleus accumbens plays important role in the acquisition and reinstatement of ethanol-seeking behavior in mice

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Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2020.112475

Abstract: Alcoholism and alcohol use disorders are chronically relapsing conditions which is a major problem in treating alcohol addiction. In a previous study we showed that the dopamine transporter (DAT) is implicated in voluntary intake and… read more here.

Keywords: acquisition reinstatement; etoh cpp; role; dat ... See more keywords
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Decellularized adipose tissue: A key factor in promoting fat regeneration by recruiting and inducing mesenchymal stem cells.

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Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.12.108

Abstract: BACKGROUND Decellularized adipose tissue (DAT) has attracted much attention due to its wide range of sources and adipose regeneration capacity. However, the lipogenic efficiency of DAT is still controversial due to its unclear mechanism. To… read more here.

Keywords: decellularized adipose; adipose regeneration; tissue; adipose tissue ... See more keywords

Combined in Vitro and in Silico Approaches to the Assessment of Stimulant Properties of Novel Psychoactive Substances

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Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.1833

Abstract: Novel psychoactive substances (NPS) are increasingly prevalent world-wide although their pharmacological characteristics are largely unknown; those with stimulant properties, due to interactions with the dopamine transporter (DAT), have addictive potential which their users may not… read more here.

Keywords: psychoactive substances; mapb; novel psychoactive; dat ... See more keywords

Duration of active psychosis and functional outcomes in first-episode non-affective psychosis

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Published in 2018 at "European Psychiatry"

DOI: 10.1016/j.eurpsy.2018.03.003

Abstract: Abstract Background: The duration of untreated psychosis (DUP) has been associated with negative outcomes in psychosis; however, few studies have focused on the duration of active psychotic symptoms after commencing treatment (DAT). In this study,… read more here.

Keywords: duration active; first episode; functional outcomes; dat ... See more keywords

Membrane cholesterol removal and replenishment affect rat and monkey brain monoamine transporters

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Published in 2018 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2018.01.039

Abstract: ABSTRACT The dopamine transporter (DAT) is abundantly expressed in the striatum where it removes extracellular dopamine into the cytosol of presynaptic nerve terminals. It is the target of drugs of abuse and antidepressants. There is… read more here.

Keywords: cholesterol; cholesterol removal; dat; membrane cholesterol ... See more keywords

Dopaminergic control of anxiety in young and aged zebrafish

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Published in 2017 at "Pharmacology Biochemistry and Behavior"

DOI: 10.1016/j.pbb.2017.01.005

Abstract: Abstract Changes in the expression of the dopamine transporter (DAT), or the sensitivity of dopamine receptors, are associated with aging and substance abuse and may underlie some of the symptoms common to both conditions. In… read more here.

Keywords: dopaminergic system; anxiety; anxiety young; anxiety like ... See more keywords