Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-024-06637-6
Abstract: We hypothesized that severe tau burden in brain regions involved in direct or indirect pathways of the basal ganglia correlate with more severe striatal dopamine deficiency in four-repeat (4R) tauopathies. Therefore, we correlated [18F]PI-2620 tau-positron-emission-tomography… read more here.
Keywords: dopamine deficiency; dat availability; 18f 2620; tau ... See more keywords
Cognitive performance correlates with the degree of dopaminergic degeneration in the associative part of the striatum in non-demented Parkinson’s patients
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DOI: 10.1007/s00702-017-1747-2
Abstract: Parkinson’s disease (PD) patients show cognitive deficits that are relevant in terms of prognosis and quality of life. Degeneration of striatal dopaminergic afferents proceeds from dorsal/caudal to anterior/ventral and is discussed to account for some… read more here.
Keywords: state; cognitive performance; striatum; performance ... See more keywords