Toxicological Properties of 7-Methylguanine, and Preliminary Data on its Anticancer Activity
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DOI: 10.3389/fphar.2022.842316
Abstract: 7-Methylguanine (7-MG) competitively inhibits the DNA repair enzyme poly(ADP-ribose) polymerase (PARP) and RNA-modifying enzyme tRNA-guanine transglycosylase (TGT) and represents a potential anticancer drug candidate. Furthermore, as a natural compound, it could escape the serious side… read more here.
Keywords: anticancer activity; toxicological properties; preliminary data; activity ... See more keywords