Use of a probabilistic PBPK/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos
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DOI: 10.1016/j.yrtph.2017.02.014
Abstract: &NA; A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model combined with Monte Carlo analysis of inter‐individual variation was used to assess the effects of the insecticide, chlorpyrifos and its active metabolite, chlorpyrifos oxon in humans.… read more here.
Keywords: biochemistry; data derived; extrapolation factors; derived extrapolation ... See more keywords