Comparison of Data Normalization Strategies for Array-Based MicroRNA Profiling Experiments and Identification and Validation of Circulating MicroRNAs as Endogenous Controls in Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.836636
Abstract: Introduction: MicroRNAs are small noncoding RNAs with potential regulatory roles in hypertension and drug response. The presence of many of these RNAs in biofluids has spurred investigation into their role as possible biomarkers for use… read more here.
Keywords: normalization strategies; hypertension; control; array based ... See more keywords
Towards Standardization of Data Normalization Strategies to Improve Urinary Metabolomics Studies by GC×GC-TOFMS
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DOI: 10.3390/metabo10090376
Abstract: Urine is a popular biofluid for metabolomics studies due to its simple, non-invasive collection and its availability in large quantities, permitting frequent sampling, replicate analyses, and sample banking. The biggest disadvantage with using urine is… read more here.
Keywords: urinary metabolomics; standardization data; data normalization; normalization ... See more keywords
Empirical evaluation of data normalization methods for molecular classification
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DOI: 10.7717/peerj.4584
Abstract: Background Data artifacts due to variations in experimental handling are ubiquitous in microarray studies, and they can lead to biased and irreproducible findings. A popular approach to correct for such artifacts is through post hoc… read more here.
Keywords: normalization methods; molecular classification; classification; accuracy ... See more keywords