Daurinoline suppressed the migration and invasion of chemo-resistant human non-small cell lung cancer cells by reversing EMT and Notch-1 and sensitized the cells to Taxol.
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DOI: 10.1016/j.etap.2018.12.005
Abstract: Non-small cell lung cancer (NSCLC) is one of the most common malignancies, and Taxol is a cornerstone in the treatment. However, taxol-resistance eventually limits the clinical effects and applications. Daurinoline could restore the sensitivity of… read more here.
Keywords: daurinoline; cell lung; chemo resistant; non small ... See more keywords