Quantification of DNA through the NanoDrop Spectrophotometer: Methodological Validation Using Standard Reference Material and Sprague Dawley Rat and Human DNA
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DOI: 10.1155/2020/8896738
Abstract: This study aimed to validate an analytical method to determine DNA concentration using standard reference material (NIST SRM 2372) and Sprague Dawley rat and human DNA. Microvolumes were used to analyse DNA samples. Linearity showed… read more here.
Keywords: reference material; standard reference; dna; using standard ... See more keywords
The Effect of Diet-induced Obesity on Toxicological Parameters in the Polygenic Sprague-Dawley Rat Model
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DOI: 10.1177/0192623318803557
Abstract: The obese rodent serves as an indispensable tool for proof-of-concept efficacy and mode-of-action pharmacology studies. Yet the utility of this disease model as an adjunct to the conventional healthy animal in the nonclinical safety evaluation… read more here.
Keywords: dawley rat; model; obesity; sprague dawley ... See more keywords
Up-regulation of MicroRNAs-21 and -223 in a Sprague-Dawley Rat Model of Traumatic Spinal Cord Injury
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DOI: 10.3390/brainsci10030141
Abstract: In this experimental animal study, we examined alterations in the degree of transcription of two microRNAs (miRs)—miR-21 and -223—in a Sprague-Dawley (SD) rat model of traumatic spinal cord injury (TSCI). Depending on the volume of… read more here.
Keywords: rat model; mir 223; model traumatic; dawley rat ... See more keywords