Central norepinephrine transmission is required for stress-induced repetitive behavior in two rodent models of obsessive-compulsive disorder
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05512-0
Abstract: Rationale Obsessive-compulsive disorder (OCD) is characterized by repetitive behaviors exacerbated by stress. Many OCD patients do not respond to available pharmacotherapies, but neurosurgical ablation of the anterior cingulate cortex (ACC) can provide symptomatic relief. Although… read more here.
Keywords: compulsive disorder; obsessive compulsive; control mice; stress induced ... See more keywords
Norepinephrine and dopamine contribute to distinct repetitive behaviors induced by novel odorant stress in male and female mice
Sign Up to like & getrecommendations! Published in 2022 at "Hormones and Behavior"
DOI: 10.1101/2022.01.25.477573
Abstract: Exposure to unfamiliar odorants induces an array of repetitive defensive and non-defensive behaviors in rodents which likely reflect adaptive stress responses to the uncertain valence of novel stimuli. Mice genetically deficient for dopamine β-hydroxylase (Dbh−/−)… read more here.
Keywords: stress; repetitive behaviors; dopamine; mice ... See more keywords