Embedded Human Closed-Loop Deep Brain Stimulation for Tourette Syndrome: A Nonrandomized Controlled Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.2741
Abstract: Importance Because Tourette syndrome (TS) is a paroxysmal disorder, symptomatic relief in individuals with TS may be possible through the application of stimulation only during the manifestation of human tic neural signatures. This technique could… read more here.
Keywords: dbs; trial; stimulation; conventional dbs ... See more keywords
Converging on a Neuromodulation Target for Tremor
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26361
Abstract: Severe action and intention tremor is one of the most common and disabling movement disorders. Often with unknown cause in essential tremor, tremor can also be a disabling symptom of Parkinson’s disease, multiple sclerosis, and… read more here.
Keywords: tremor; dbs; lesion based; vim ... See more keywords
The optimal target and connectivity for DBS in Lennox-Gastaut syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of neurology"
DOI: 10.1002/ana.26368
Abstract: OBJECTIVE Deep brain stimulation (DBS) can reduce seizures in Lennox-Gastaut syndrome (LGS). However, little is known about the optimal target and whether efficacy depends on connectivity of the stimulation site. Using outcome data from the… read more here.
Keywords: connectivity dbs; optimal target; dbs; connectivity ... See more keywords
Persistent Racial Disparities in Deep Brain Stimulation for Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26378
Abstract: We sought to determine whether racial and socioeconomic disparities in the utilization of deep brain stimulation (DBS) for Parkinson's disease (PD) have improved over time. We examined DBS utilization and analyzed factors associated with placement… read more here.
Keywords: deep brain; dbs; parkinson disease; brain stimulation ... See more keywords
Analysis of dried blood spots is a feasible alternative for detecting ephedrine in doping control.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3338
Abstract: Dried blood spot (DBS) testing allows fast, easy, and minimally invasive collection of microvolumes of blood. In an anti-doping context, DBS testing has particular relevance for substances prohibited in-competition only such as ephedrine, which is… read more here.
Keywords: dbs; doping control; dried blood; analysis ... See more keywords
Long‐term ANT‐DBS effects in pilocarpine‐induced epileptic rats: A combined 9.4T MRI and histological study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25169
Abstract: Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) appears to be effective against seizures in animals and humans however, its therapeutic mechanisms remain elusive. This study aimed to combine 9.4T multimodal… read more here.
Keywords: epileptic rats; long term; dbs; ant dbs ... See more keywords
Challenges in PD Patient Management After DBS: A Pragmatic Review
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.12592
Abstract: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or internal globus pallidus (GPi) represents an effective and universally applied therapy for Parkinson's disease (PD) motor complications. However, certain procedure‐related problems and unrealistic patient expectations… read more here.
Keywords: management dbs; pragmatic review; challenges patient; patient management ... See more keywords
Fading of Deep Brain Stimulation Efficacy Versus Disease Progression: Untangling a Gordian Knot
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13041
Abstract: Parkinson’s disease (PD) is a relentlessly progressive neurodegenerative disorder leading to increasingly motor and nonmotor disabling symptoms with a substantial risk of functional decline and reduced life expectancy. Since its approval for treating PD, deep… read more here.
Keywords: long term; disease; dbs; motor ... See more keywords
Strategic Utilization of Next‐Generation Deep Brain Stimulation Pulse Generators
Sign Up to like & getrecommendations! Published in 2023 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13689
Abstract: Deep brain stimulation (DBS) is a well-established treatment for movement disorders. Recent industrial competition has led to unprecedented new technologic implementation. Nextgeneration implantable pulse generators (IPGs), henceforth defined as FDA-approved devices after 2015, include Abbott… read more here.
Keywords: boston; dbs; boston scientific; next generation ... See more keywords
An update on adaptive deep brain stimulation in Parkinson's disease
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.115
Abstract: Advancing conventional open‐loop DBS as a therapy for PD is crucial for overcoming important issues such as the delicate balance between beneficial and adverse effects and limited battery longevity that are currently associated with treatment.… read more here.
Keywords: stimulation; parkinson; input signals; dbs ... See more keywords
Deep brain stimulation modulates the shape of cortical beta oscillations in Parkinson's disease
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.27144
Abstract: Deep brain stimulation (DBS) is now a common treatment for moderate to advanced Parkinson’s disease (PD), yet its mechanisms of action and how it interacts with PD pathophysiology are not well understood. It has been… read more here.
Keywords: stimulation; beta; beta oscillations; dbs ... See more keywords