DBU-promoted tandem Michael-addition/cyclization for the synthesis of polysubstituted pyrroles
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DOI: 10.1016/j.tet.2019.02.057
Abstract: Abstract An efficient and transition-metal-free method for the synthesis of the structurally diversified pyrroles is described. Various α,β-unsaturated ynones reacted with N-substituted ethyl glycine ethyl ester hydrochlorides in the presence of DBU to form the… read more here.
Keywords: synthesis; promoted tandem; polysubstituted pyrroles; synthesis polysubstituted ... See more keywords
DBU-Promoted Cu(OAc)•H2O-Catalysed Coupling Reactions of Aryl Iodides and Sodium Azide
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DOI: 10.3184/174751918x15260507766192
Abstract: An efficient and simple protocol for the synthesis of aryl azides by the coupling of aryl iodides with sodium azide, in good to excellent yields in DMSO at 95 °C under catalysis by Cu(OAc)2-H2O and… read more here.
Keywords: sodium azide; aryl iodides; iodides sodium; dbu promoted ... See more keywords
DBU Promoted Polysubstituted Arene Formation via a Michael Addition/Cyclization/Elimination Cascade Reaction
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DOI: 10.3390/molecules27238167
Abstract: The straightforward construction of polysubstituted arenes is essential in both synthetic chemistry and medicinal chemistry. Herein, we reported a DBU promoted Michael addition/cyclization/elimination cascade reaction between vinylogous malononitrile derivatives and chlorinated nitrostyrenes for the synthesis… read more here.
Keywords: reaction; cascade; chemistry; michael addition ... See more keywords
DABCO- and DBU-promoted one-pot reaction of N-sulfonyl ketimines with Morita–Baylis–Hillman carbonates: a sequential approach to (2-hydroxyaryl)nicotinate derivatives
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DOI: 10.3762/bjoc.14.254
Abstract: An intriguing DABCO-catalyzed and DBU-promoted one-pot synthesis of an important class of (2-hydroxyaryl)pyridine derivatives bearing a carboxylate or a nitrile group suitably placed at C3 position of the aza-ring has been achieved in acceptable chemical… read more here.
Keywords: hydroxyaryl; one pot; promoted one; dbu promoted ... See more keywords
Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin
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DOI: 10.3762/bjoc.16.46
Abstract: The synthetic utility of pterins is often hampered by the notorious insolubility of this heterocycle, slowing the development of medicinally relevant pteridine derivatives. Reactions which expedite the development of new pterins are thus of great… read more here.
Keywords: promoted amidations; exploring scope; scope; dbu ... See more keywords