Whole exome sequencing reveals novel NOV and DCAF13 variants in a Chinese pedigree with familial cortical myoclonic tremor with epilepsy
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.07.014
Abstract: OBJECTIVE We report a large new family of familial cortical myoclonic tremor with epilepsy(FCMTE) from China and identify the possible causative gene(s) for the family. METHOD Whole exome sequencing of blood genomic DNA from 4… read more here.
Keywords: myoclonic tremor; familial cortical; cortical myoclonic; family ... See more keywords
DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer science"
DOI: 10.1111/cas.15300
Abstract: Evolutionarily conserved DDB1-and CUL4-associated factor 13 (DCAF13) is a recently discovered substrate receptor for the cullin RING-finger ubiquitin ligase 4 (CRL4) E3 ubiquitin ligase that regulates cell cycle progression. DCAF13 is overexpressed in many cancers,… read more here.
Keywords: cancer; cancer cell; breast cancer; proliferation ... See more keywords
The overexpression and prognostic role of DCAF13 in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317705753
Abstract: DDB1 and CUL4 associated factor 13 (DCAF13) is a protein coding gene located on chromosome 8q22.3, which is a hotspot amplified in various cancers. DCAF13 has been reported to be frequently amplified in breast cancer… read more here.
Keywords: hepatocellular carcinoma; dcaf13 hepatocellular; role dcaf13; dcaf13 ... See more keywords