Abstract 3424: Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders
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DOI: 10.1158/1538-7445.am2023-3424
Abstract: Molecular glue degraders have emerged as a powerful class of small-molecule therapeutics, as demonstrated by the clinical successes of thalidomide analogs in the treatment of hematological malignancies. These small molecules act by recruiting ubiquitin ligases… read more here.
Keywords: dcaf16; glue degraders; covalent modification; molecular glue ... See more keywords