CRISPRi-dCas12a: A dCas12a-mediated CRISPR interference for repression of multiple genes and metabolic engineering in cyanobacteria.
Sign Up to like & getrecommendations! Published in 2020 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.0c00091
Abstract: In cyanobacteria, metabolic engineering using synthetic biology tools is limited to build a bio-solar cell factory that converts CO2 to value-added chemicals, as repression of essential genes has not been achieved. In this study, we… read more here.
Keywords: dcas12a; metabolic engineering; repression; biology ... See more keywords
CRISPR/dCas12a-mediated activation of SlPAL2 enhances tomato resistance against bacterial canker disease
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0320436
Abstract: Crop protection is essential for maintaining and improving agricultural productivity. While pesticides are commonly used to control pests, they pose several challenges, including environmental harm and health risks. Alternative strategies to pesticides include breeding resistant… read more here.
Keywords: resistance; dcas12a; activation; crop ... See more keywords