Articles with "dcas9 based" as a keyword



Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system

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Published in 2019 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkz709

Abstract: Abstract Establishing causal relationship between epigenetic marks and gene transcription requires molecular tools, which can precisely modify specific genomic regions. Here, we present a modular and extensible CRISPR/dCas9-based toolbox for epigenetic editing and direct gene… read more here.

Keywords: dcas9; system; dcas9 based; gene ... See more keywords