Paired Design of dCas9 as a Systematic Platform for the Detection of Featured Nucleic Acid Sequences in Pathogenic Strains.
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DOI: 10.1021/acssynbio.6b00215
Abstract: We developed an in vitro DNA detection system using a pair of dCas9 proteins linked to split halves of luciferase. Luminescence was induced upon colocalization of the reporter pair to a ∼44 bp target sequence… read more here.
Keywords: detection; design dcas9; paired design; dcas9 systematic ... See more keywords