Small-Molecule-Mediated Split-Aptamer Assembly for Inducible CRISPR-dCas9 Transcription Activation.
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DOI: 10.1021/acschembio.2c00101
Abstract: Inducible CRISPR-dCas9 transcription system has become a powerful tool for transcription regulation and sensing. Here, we develop a new concept of small-molecule-mediated split-aptamer assembly for inducible CRISPR-dCas9 transcription activation, allowing quantitative detection and imaging of… read more here.
Keywords: inducible crispr; dcas9 transcription; transcription; dcas9 ... See more keywords