Comparative analysis of dCas9-VP64 variants and multiplexed guide RNAs mediating CRISPR activation
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DOI: 10.1371/journal.pone.0270008
Abstract: CRISPR/Cas9-mediated transcriptional activation (CRISPRa) is a powerful tool for investigating complex biological phenomena. Although CRISPRa approaches based on the VP64 transcriptional activator have been widely studied in both cultured cells and in animal models and… read more here.
Keywords: dcas9 vp64; activation; crispra; dcas9 ... See more keywords