Deoxycholylglycine, a conjugated secondary bile acid, reduces vascular tone by attenuating Ca2+ sensitivity via rho kinase pathway
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.04.012
Abstract: ABSTRACT Patients with cirrhosis have reduced systemic vascular resistance and elevated circulating bile acids (BAs). Previously, we showed that secondary conjugated BAs impair vascular tone by reducing vascular smooth muscle cell (VSMC) Ca2+ influx. In… read more here.
Keywords: ca2 sensitivity; tone; vascular tone; vasoconstriction ... See more keywords
Altered regional gray matter volume in Chinese female patients with bulimia nervosa
Sign Up to like & getrecommendations! Published in 2020 at "BMC Psychiatry"
DOI: 10.1186/s12888-020-02493-4
Abstract: Background Bulimia nervosa (BN) is a psychiatric disorder with unclear pathophysiology. Several studies have associated BN with structural and functional changes in the brain, but findings have been inconsistent. Here we explored this potential association… read more here.
Keywords: dcg; matter volume; gmv; bulimia nervosa ... See more keywords