Articles with "dck negatively" as a keyword



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dCK negatively regulates the NRF2/ARE axis and ROS production in pancreatic cancer

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Published in 2018 at "Cell Proliferation"

DOI: 10.1111/cpr.12456

Abstract: Decreased deoxycytidine kinase (dCK) expression is a reported indicator of gemcitabine efficacy in pancreatic cancer, due to the impact of this kinase on gemcitabine metabolism. The transcription factor NF‐E2 p45‐related factor 2 (NRF2, also called… read more here.

Keywords: dck; negatively regulates; pancreatic cancer; regulates nrf2 ... See more keywords