Articles with "dcn" as a keyword



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Functional organization and connectivity of the dorsal column nuclei complex reveals a sensorimotor integration and distribution hub

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Published in 2020 at "Journal of Comparative Neurology"

DOI: 10.1002/cne.24942

Abstract: The dorsal column nuclei complex (DCN‐complex) includes the dorsal column nuclei (DCN, referring to the gracile and cuneate nuclei collectively), external cuneate, X, and Z nuclei, and the median accessory nucleus. The DCN are organized… read more here.

Keywords: dcn; nuclei; sensorimotor; organization connectivity ... See more keywords
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Fabrication of novel elastosomes for boosting the transdermal delivery of diacerein: statistical optimization, ex-vivo permeation, in-vivo skin deposition and pharmacokinetic assessment compared to oral formulation

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Published in 2018 at "Drug Delivery"

DOI: 10.1080/10717544.2018.1451572

Abstract: Abstract Diacerein (DCN) is a hydrophobic osteoarthritis (OA) drug with short half-life and low oral bioavailability. Furthermore, DCN oral administration is associated with diarrhea which represents obstacle against its oral use. Hence, this article aimed… read more here.

Keywords: transdermal delivery; vivo; dcn; drug ... See more keywords
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Novel DCN Mutation in Armenian Family With Congenital Stromal Corneal Dystrophy

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Published in 2022 at "Cornea"

DOI: 10.1097/ico.0000000000003167

Abstract: Supplemental Digital Content is Available in the Text. Purpose: Congenital stromal corneal dystrophy (CSCD) is a rare congenital, dominantly inherited disorder characterized by diffuse stromal opacification associated with mutations in the decorin gene (DCN). As… read more here.

Keywords: family; cscd; congenital stromal; corneal ... See more keywords
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Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.

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Published in 2022 at "Pain"

DOI: 10.1097/j.pain.0000000000002806

Abstract: ABSTRACT Descending control of nociception (DCN; also known as conditioned pain modulation [CPM], the behavioral correlate of diffuse noxious inhibitory controls) is the phenomenon whereby pain inhibits pain in another part of the body and… read more here.

Keywords: hyperalgesic dcn; descending control; dcn; pain ... See more keywords
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While Urine and Plasma Decorin Remain Unchanged in Prostate Cancer, Prostatic Tissue Decorin Has a Prognostic Value.

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Published in 2020 at "Iranian biomedical journal"

DOI: 10.29252/ibj.24.4.229

Abstract: Background Numerous studies confirmed significant decrease in tissue DCN expression is associated to tumor progression and metastasis in certain types of cancer including PC. However, the potential prognostic value of tissue DCN in PC has… read more here.

Keywords: plasma; value; tissue; dcn ... See more keywords
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Decorin–induced, preeclampsia-associated microRNA-512-3p restrains extravillous trophoblast functions by targeting USF2/PPP3R1 axis

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.1014672

Abstract: Decorin (DCN) is a leucine-rich proteoglycan produced by chorionic villus mesenchymal cells anddecidual cells during human pregnancy. Studies from our laboratory demonstrated that decidua-derived DCN restrains multiple trophoblast functions including proliferation, migration, invasion andendovascular differentiation,… read more here.

Keywords: mir 512; decorin; trophoblast functions; dcn ... See more keywords
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High Proteoglycan Decorin Levels Are Associated With Acute Coronary Syndrome and Provoke an Imbalanced Inflammatory Response

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Published in 2021 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2021.746377

Abstract: Background and Aims: Acute coronary syndrome (ACS) has become one of the most common causes of disability. It is thus important to identify ACS early in the disease course of patients using novel biomarkers for… read more here.

Keywords: inflammatory response; dcn; acute coronary; coronary syndrome ... See more keywords
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Focusing on the Emerging Role of Kainate Receptors in the Dorsal Cochlear Nucleus (DCN) and Cerebellum

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24021718

Abstract: Mammals have a dorsal cochlear nucleus (DCN), which is thought to be a cerebellum-like structure with similar features in terms of structure and microcircuitry to the cerebellum. Both the DCN and cerebellum perform their functions… read more here.

Keywords: role; cochlear nucleus; dcn cerebellum; dcn ... See more keywords