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Published in 2017 at "Molecular Neurodegeneration"
DOI: 10.1186/s13024-017-0173-0
Abstract: BackgroundMicroglia mediate amyloid-beta peptide (Aβ)-induced neuroinflammation, which is one of the key events in the pathogenesis of Alzheimer’s disease (AD). Decoy receptor 3 (DcR3)/TNFRSF6B is a pleiotropic immunomodulator that promotes macrophage differentiation toward the M2…
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Keywords:
amelioration amyloid;
alzheimer disease;
app;
dcr3 ... See more keywords
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Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.638676
Abstract: Gout is a common inflammatory arthritis caused by the deposition of monosodium urate (MSU) crystals in the joints. This activates the macrophages into a proinflammatory state by inducing NLRP3-dependent interleukin-1β (IL-1β) secretion, resulting in neutrophil…
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Keywords:
inflammasome activation;
dcr3;
activation;
nlrp3 inflammasome ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.879648
Abstract: Background Decoy receptor 3 (DcR3) belongs to the tumor necrosis factor (TNF) receptor superfamily and neutralizes TNF ligands, including FasL and TRAIL, to prevent T activation during T-cell priming. However, the cellular mechanisms underlying acute…
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Keywords:
cell;
dcr3;
acute cell;
cell priming ... See more keywords
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Published in 2018 at "Chinese Medical Journal"
DOI: 10.4103/0366-6999.221271
Abstract: Background: Decoy receptor 3 (DcR3) is a protein with anti-apoptotic effect that belongs to the tumor necrosis factor receptor superfamily. DcR3 is highly expressed in a variety of malignant tumors including cholangiocarcinoma and its expression…
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Keywords:
cell line;
cell;
cholangiocarcinoma;
dcr3 ... See more keywords