Surface engineered polymersomes for enhanced modulation of dendritic cells during cardiovascular immunotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced functional materials"
DOI: 10.1002/adfm.201904399
Abstract: The principle cause of cardiovascular disease (CVD) is atherosclerosis, a chronic inflammatory condition characterized by immunologically complex fatty lesions within the intima of arterial vessel walls. Dendritic cells (DCs) are key regulators of atherosclerotic inflammation,… read more here.
Keywords: dcs; surface; dendritic cells; engineered polymersomes ... See more keywords
Antigen‐Free Radionuclide‐Embedded Gold Nanoparticles for Dendritic Cell Maturation, Tracking, and Strong Antitumor Immunity
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201701369
Abstract: Dendritic cell (DC)-based cancer immunotherapy requires efficient maturation of DCs and sensitive monitoring of DCs localized in the lymph nodes that activate T cells. This paper reports a robust and simple surface chemistry for highly… read more here.
Keywords: embedded gold; dcs; chemistry; maturation ... See more keywords
Mouse dendritic cells in the steady state: Hypoxia, autophagy, and stem cell factor
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3737
Abstract: Dendritic cells (DCs) are innate immune cells with a central role in immunity and tolerance. Under steady‐state, DCs are scattered in tissues as resting cells. Upon infection or injury, DCs get activated and acquire the… read more here.
Keywords: cell; dcs; hypoxia; factor ... See more keywords
Modulation of CD11c+ lung dendritic cells in respect to TGF‐β in experimental pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10800
Abstract: Idiopathic pulmonary fibrosis (IPF) is a deadly, progressive lung disease with very few treatment options till now. Bleomycin‐induced pulmonary fibrosis (BIPF) is a commonly used mice model in IPF research. TGF‐β1 has been shown to… read more here.
Keywords: cd11c; dcs; tgf; pulmonary fibrosis ... See more keywords
Spreading the load: Antigen transfer between migratory and lymph node‐resident dendritic cells promotes T‐cell priming
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201747248
Abstract: Dendritic cells (DC) are specialized in the processing and presentation of antigen for the activation of lymphocytes. Multiple subsets of DCs exist with distinct functions and roles in the initiation of immune responses. DCs found… read more here.
Keywords: dcs; lymph; dendritic cells; antigen ... See more keywords
Lipopolysaccharide impacts murine CD103+ DC differentiation, altering the lung DC population balance
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Immunology"
DOI: 10.1002/eji.201847910
Abstract: Conventional DCs are a heterogeneous population that bridge the innate and adaptive immune systems. The lung DC population comprises CD103+XCR1+ DC1s and CD11b+ DC2s; their various combined functions cover the whole spectrum of immune responses… read more here.
Keywords: capacity; lung population; dcs; xcr1 dcs ... See more keywords
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149733
Abstract: It is commonly believed that IL‐12 produced by DCs in response to pathogens is the first signal that stimulates the production of IFN‐γ by NK cells. However, IL‐12 production by DCs in response to bacterial… read more here.
Keywords: dcs; ifn production; production; production cells ... See more keywords
Invasive versus non‐invasive mapping of the motor cortex
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25101
Abstract: Abstract Precise and comprehensive mapping of somatotopic representations in the motor cortex is clinically essential to achieve maximum resection of brain tumours whilst preserving motor function, especially since the current gold standard, that is, intraoperative… read more here.
Keywords: invasive versus; mapping; dcs; non invasive ... See more keywords
Monocytes complexed to platelets differentiate into functionally deficient dendritic cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3a0620-460rr
Abstract: In addition to their role in hemostasis, platelets store numerous immunoregulatory molecules such as CD40L, TGFβ, β2‐microglobulin, and IL‐1β and release them upon activation. Previous studies indicate that activated platelets form transient complexes with monocytes,… read more here.
Keywords: activated platelets; dcs; dendritic cells; complexed platelets ... See more keywords
Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0290-4_16
Abstract: When introduced into endosomes via cationic lipids, certain small interfering RNA (siRNA) sequences activate the interferon signaling pathways in immune cells such as dendritic cells (DCs), known as the most efficient antigen-presenting cells of the immune… read more here.
Keywords: dcs; immunostimulatory sirnas; type responses; antiviral type ... See more keywords
Method of Generating Tolerogenic Maturation-Resistant Dendritic Cells and Testing for Their Immune-Regulatory Functions In Vivo in the Context of Transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8938-6_13
Abstract: During that past two decades, advances in techniques for generating in vitro immune-suppressive dendritic cells (DCs) have heralded the use of these pro-tolerogenic DCs as therapeutics against transplant rejection and autoimmune diseases. In transplantation, previous… read more here.
Keywords: dcs; donor; dendritic cells; maturation ... See more keywords