Novel lissencephaly‐associated DCX variants in the C‐terminal DCX domain affect microtubule binding and dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17198
Abstract: Pathogenic variants in DCX on the X chromosome lead to lissencephaly and subcortical band heterotopia (SBH), brain malformations caused by neuronal migration defects. Its product doublecortin (DCX) binds to microtubules to modulate microtubule polymerization. How… read more here.
Keywords: variants terminal; novel lissencephaly; dcx; associated dcx ... See more keywords