Articles with "ddhctp" as a keyword



Viral RNA Replication Suppression of SARS-CoV-2: Atomistic Insights into Inhibition Mechanisms of RdRp Machinery by ddhCTP

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Published in 2024 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.3c01919

Abstract: The nonstructural protein 12, known as RNA-dependent RNA polymerase (RdRp), is essential for both replication and repair of the viral genome. The RdRp of SARS-CoV-2 has been used as a promising candidate for drug development… read more here.

Keywords: sars cov; ddhctp; rna; rna replication ... See more keywords