Ticagrelor and Statins: Dangerous Liaisons?
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-024-07624-7
Abstract: Polypharmacy is often necessary in complex, chronic, comorbid and cardiovascular patients and is a known risk factor for potential drug-drug interaction (DDI) that can cause adverse reactions (toxicity or therapeutic failure). Anti-thrombotic drugs (largely low-dose… read more here.
Keywords: statins dangerous; ddi; dangerous liaisons; drug ... See more keywords
Use of a Caco-2 permeability assay to evaluate the effects of several Kampo medicines on the drug transporter P-glycoprotein
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1222-x
Abstract: In modern medical care in which Kampo and Western drugs are often combined, it is extremely important to clarify drug–drug interaction (DDI) to ensure safety and efficacy. However, there is little evidence of DDI in… read more here.
Keywords: five kampo; kampo medicines; drug; transporter glycoprotein ... See more keywords
Regulating the alky chain length of fatty acid-didanosine prodrugs and evaluating its role in albumin binding
Sign Up to like & getrecommendations! Published in 2017 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-017-0428-x
Abstract: Rational design of prodrugs for efficient albumin binding shows distinct advantages in drug delivery in terms of drug availability, systemic circulation, and potential targeting effect. And fatty acids are good candidates due to their high… read more here.
Keywords: chain length; acid didanosine; ddi;
Surface amplification of pencil graphite electrode with polypyrrole and reduced graphene oxide for fabrication of a guanine/adenine DNA based electrochemical biosensors for determination of didanosine anticancer drug
Sign Up to like & getrecommendations! Published in 2018 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2018.01.237
Abstract: Abstract Didanosine is nucleoside analog reverse transcriptase inhibitors with many side effects such as nausea and vomiting, stomach pain, tingling, burning and numbness and determination of this drug is very important in biological samples. This… read more here.
Keywords: ppy rgo; rgo; pge ppy; dna ... See more keywords
Control over Phase Transformations in a Family of Flexible Double Diamondoid Coordination Networks through Linker Ligand Substitution
Sign Up to like & getrecommendations! Published in 2023 at "Chemistry of Materials"
DOI: 10.1021/acs.chemmater.3c00334
Abstract: In this work, we present the first metal–organic framework (MOF) platform with a self-penetrated double diamondoid (ddi) topology that exhibits switching between closed (nonporous) and open (porous) phases induced by exposure to gases. A crystal… read more here.
Keywords: topology; coordination; double diamondoid; ddi ... See more keywords
A large cross-sectional study on the prevalence and predictors of donor and donation images in patients after heart transplantation
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-07317-7
Abstract: Recovery and clinical outcomes following organ transplantation may be negatively influenced by psychological distress. Limited reports from recipients indicate that thoughts and feelings related to the donor/transplanted organ – referred to as donor and donation… read more here.
Keywords: ddi; donation images; patients heart; donor donation ... See more keywords
Update on drug interactions with non-vitamin-K-antagonist oral anticoagulants for stroke prevention in elderly patients
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2021.1908124
Abstract: ABSTRACT Introduction: We update the knowledge, since the last review in 2017, about drug–drug interactions (DDI) of non-vitamin-K-antagonist oral anticoagulants (NOAC) in patients ≥75 years. Areas covered: The literature was searched for: ‘dabigatran,’ ‘rivaroxaban,’ ‘edoxaban,’… read more here.
Keywords: non vitamin; drug interactions; elderly patients; ddi ... See more keywords
R2-DDI: relation-aware feature refinement for drug-drug interaction prediction
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac576
Abstract: Precisely predicting the drug-drug interaction (DDI) is an important application and host research topic in drug discovery, especially for avoiding the adverse effect when using drug combination treatment for patients. Nowadays, machine learning and deep… read more here.
Keywords: feature refinement; drug drug; ddi; prediction ... See more keywords
IK-DDI: a novel framework based on instance position embedding and key external text for DDI extraction.
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbad099
Abstract: Determining drug-drug interactions (DDIs) is an important part of pharmacovigilance and has a vital impact on public health. Compared with drug trials, obtaining DDI information from scientific articles is a faster and lower cost but… read more here.
Keywords: information; extraction; framework; external text ... See more keywords
Benchmarking drug–drug interaction prediction methods: a perspective of distribution changes
Sign Up to like & getrecommendations! Published in 2024 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaf569
Abstract: Abstract Motivation Emerging drug–drug interaction (DDI) prediction is crucial for new drugs but is hindered by distribution changes between known and new drugs in real-world scenarios. Current evaluation often neglects these changes, relying on unrealistic… read more here.
Keywords: distribution changes; ddi; distribution; drug drug ... See more keywords
Spleen stiffness measurements using point shear wave elastography detects noncirrhotic portal hypertension in human immunodeficiency virus
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017961
Abstract: Abstract To assess the utility of spleen stiffness as a diagnostic tool in individuals with human immunodeficiency virus (HIV) and non-cirrhotic portal hypertension (NCPH). The Philips EPIQ7, a new point shearwave elastography (pSWE) technique, was… read more here.
Keywords: spleen stiffness; portal hypertension; immunodeficiency virus; stiffness ... See more keywords