Xanthatin induce DDP-resistance lung cancer cells apoptosis through regulation of GLUT1 mediated ROS accumulation.
Sign Up to like & getrecommendations! Published in 2023 at "Drug development research"
DOI: 10.1002/ddr.22084
Abstract: Chemoresistance to cisplatin (DDP) therapy is a major obstacle that needs to be overcome in treating lung cancer patients. Xanthatin has been reported to exhibit an antitumor effect on various cancers, but the function of… read more here.
Keywords: lung cancer; ddp; ddp resistance;
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114741
Abstract: The resistance to cisplatin (DDP) and dose-related toxicity are the two important obstacles in the chemotherapy of prostate cancer (PCa) patients. The present study demonstrated that cotreatment of DDP and RSL3, a type of small… read more here.
Keywords: glycolysis dysfunction; ddp; prostate cancer; rsl3 ... See more keywords
Synergistic effects of silver nanoparticles and cisplatin in combating inflammation and hyperplasia of airway stents
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.07.029
Abstract: Anti-inflammatory and antihyperplasia activities are essential requirements for the successful use of airway stents. In this work, silver nanoparticles (AgNPs) and cisplatin (DDP) were combined in a synergistic modification strategy to improve the surface function… read more here.
Keywords: airway stents; silver nanoparticles; ddp; dual functional ... See more keywords
Isovitexin potentiated the antitumor activity of cisplatin by inhibiting the glucose metabolism of lung cancer cells and reduced cisplatin-induced immunotoxicity in mice.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107357
Abstract: The increased resistance and toxicity have become the main causes of chemotherapy failure for treating lung cancer. The combination of chemotherapeutic drugs with other agents has been recognized as a promising strategy to overcome these… read more here.
Keywords: ddp; cisplatin; mice; lung cancer ... See more keywords
MicroRNA-106a-5p alleviated the resistance of cisplatin in lung cancer cells by targeting Jumonji domain containing 6.
Sign Up to like & getrecommendations! Published in 2021 at "Transplant immunology"
DOI: 10.1016/j.trim.2021.101478
Abstract: BACKGROUND Cisplatin (DDP) is used for lung cancer therapy. MicroRNAs, small non-coding RNAs, may contribute to tumorigenesis as well as to drug resistance. We examined regulatory functions of miR-106a-5p in DDP-resistant lung cancer cells. METHODS… read more here.
Keywords: lung cancer; ddp; mir 106a; apoptosis ... See more keywords
A Strategy to Delay the Development of Cisplatin Resistance by Maintaining a Certain Amount of Cisplatin-Sensitive Cells
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DOI: 10.1038/s41598-017-00422-2
Abstract: Cisplatin (ddp), which is commonly employed in the treatment of many advanced cancers, often results in initial therapeutic success; however, rapid progression of ddp-resistant cells remains the main reason for treatment failure. Facd with such… read more here.
Keywords: resistant cells; ddp; treatment; cisplatin ... See more keywords
Interaction of dicoordinate phosphorus with boranes: chemistry of 3a,6a-diaza-1,4-diphosphapentalene as masked phosphinidene.
Sign Up to like & getrecommendations! Published in 2021 at "Dalton transactions"
DOI: 10.1039/d1dt00747e
Abstract: Treatment of 3a,6a-diaza-1,4-diphosphapentalene (DDP) with an excess of PhBCl2 yields the corresponding bis(borane) adduct DDP(PhBCl2)2 (14), demonstrating the availability of two lone pairs on the phosphorus center. The reaction between DDP and B(C6F5)3 yields (1 : 1)… read more here.
Keywords: diaza diphosphapentalene; ddp; masked phosphinidene; chemistry ... See more keywords
Controllable fabrication of a hybrid containing dodecyl dihydrogen phosphate modified magnesium borate whisker/hydrated alumina for enhancing the fire safety and mechanical properties of epoxy resin
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DOI: 10.1039/d1ra08289b
Abstract: A composite particle with hydrated alumina deposited on the surface of magnesium borate whisker (MBW@HA) was prepared following a chemical liquid deposition method. Subsequently, dodecyl dihydrogen phosphate (DDP) was grafted onto the surface of the… read more here.
Keywords: mbw ddp; ddp; fire safety; mechanical properties ... See more keywords
NORAD accelerates chemo-resistance of non-small-cell lung cancer via targeting at miR-129-1-3p/SOX4 axis
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DOI: 10.1042/bsr20193489
Abstract: Abstract Substantial researches indicated that long non-coding RNAs (lncRNAs) exerted profound effects on chemo-resistance in cancer treatment. Nonetheless, the role of NORAD in non-small-cell lung cancer (NSCLC) remains unclear. In the present study, we chose… read more here.
Keywords: chemo resistance; cancer; cell; mir 129 ... See more keywords
PRPS2 Enhances Resistance to Cisplatin via Facilitating Exosomes-mediated Macrophage M2 Polarization in Non-small Cell Lung Cancer.
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DOI: 10.1080/08820139.2021.1952217
Abstract: Background: Phosphoribosyl pyrophosphate synthetases 2 (PRPS2) is reported as an oncogene in various cancers. However, the role of PRPS2 in cisplatin (DDP) resistance of non-small cell lung cancer (NSCLC) remains unclear. The present study aimed… read more here.
Keywords: prps2; ddp; macrophage polarization; resistance ... See more keywords
Circ_0067934 reduces JNK phosphorylation through a microRNA-545-3p/PPA1 axis to enhance tumorigenesis and cisplatin resistance in ovarian cancer
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2038193
Abstract: Abstract Background Circular RNA 0067934 (circ_0067934) has been revealed as a cancer driver in multiple human malignancies, whereas its action in the pathogenesis of ovarian cancer (OC) remains unclear. This study focuses on the function… read more here.
Keywords: mir 545; resistance; circ 0067934; ddp ... See more keywords