Xanthatin induce DDP-resistance lung cancer cells apoptosis through regulation of GLUT1 mediated ROS accumulation.
Sign Up to like & getrecommendations! Published in 2023 at "Drug development research"
DOI: 10.1002/ddr.22084
Abstract: Chemoresistance to cisplatin (DDP) therapy is a major obstacle that needs to be overcome in treating lung cancer patients. Xanthatin has been reported to exhibit an antitumor effect on various cancers, but the function of… read more here.
Keywords: lung cancer; ddp; ddp resistance;
Circ_0076305 regulates cisplatin resistance of non-small cell lung cancer via positively modulating STAT3 by sponging miR-296-5p.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116984
Abstract: AIMS Circular RNAs (circRNAs) acted as key regulators in the development of various human tumors. Our present study aimed to investigate the role and molecular mechanism of circ_0076305 in regulating cisplatin (DDP) resistance of non-small… read more here.
Keywords: mir 296; ddp resistance; stat3; circ 0076305 ... See more keywords
Exosome-transmitted circVMP1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting miR-524-5p-METTL3/SOX2 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Drug delivery"
DOI: 10.1080/10717544.2022.2057617
Abstract: BACKGROUND Circular RNAs (circRNAs) play important regulatory roles in multiple human malignancies, including non-small cell lung cancer (NSCLC). Here, we explored the role of circRNA vacuole membrane protein 1 (circVMP1) in NSCLC progression and cisplatin… read more here.
Keywords: ddp resistance; circvmp1; resistance; mir 524 ... See more keywords
Cancer-associated fibroblast exosomes promote chemoresistance to cisplatin in hepatocellular carcinoma through circZFR targeting signal transducers and activators of transcription (STAT3)/ nuclear factor -kappa B (NF-κB) pathway
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2032972
Abstract: ABSTRACT Chemoresistance in hepatocellular carcinoma (HCC) has been found to be influenced by exosomal transport of circRNAs. However, the role of circZFR in HCC chemoresistance still remains unclear. In the present study, circZFR was highly… read more here.
Keywords: hepatocellular carcinoma; ddp resistance; hcc; cancer associated ... See more keywords
Circulating exosomal circFoxp1 confers cisplatin resistance in epithelial ovarian cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gynecologic Oncology"
DOI: 10.3802/jgo.2020.31.e75
Abstract: Objective Early detection and treatment are particularly important to epithelial ovarian cancer (EOC). Studies have shown that circular RNA (circRNA) dysregulation is associated with the proliferation and metastasis of ovarian cancer cells. This study focused… read more here.
Keywords: circulating exosomal; circfoxp1; ddp resistance; exosomal circfoxp1 ... See more keywords
Brother of regulator of imprinted sites inhibits cisplatin-induced DNA damage in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.12114
Abstract: Cisplatin (DDP) chemotherapy is the primary modality of treatment for non-small cell lung cancer (NSCLC). However, due to the occurrence of DDP resistance, only a limited number of patients benefit from this treatment regimen. Brother… read more here.
Keywords: dna damage; induced dna; boris; ddp resistance ... See more keywords
Long non-coding RNA SNHG1 contributes to cisplatin resistance in non-small cell lung cancer by regulating miR-140-5p/Wnt/β-catenin pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Neoplasma"
DOI: 10.4149/neo_2018_181218n980
Abstract: Small nucleolar RNA host gene 1 (SNHG1) has been identified to function as an oncogene in a large number of human cancers. Nevertheless, the biologic role and underlying molecular mechanism of SNHG1 on cisplatin (DDP)-resistance… read more here.
Keywords: ddp resistance; snhg1; mir 140; resistance ... See more keywords