Resistance to DNA repair inhibitors in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13224
Abstract: The DNA damage response (DDR) represents a complex network of proteins which detect and repair DNA damage, thereby maintaining the integrity of the genome and preventing the transmission of mutations and rearranged chromosomes to daughter… read more here.
Keywords: resistance; ddr; cancer; resistance dna ... See more keywords
Histology of the distal dural ring
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Anatomy"
DOI: 10.1002/ca.22916
Abstract: The distal dural ring (DDR) is a conserved intracranial anatomic structure marking the boundary point at which the internal carotid artery (ICA) exits the cavernous sinus (CS) and enters the subarachnoid space. Although the CS… read more here.
Keywords: dural ring; ica ddr; ddr; distal dural ... See more keywords
The DNA damage response pathway in normal hematopoiesis and malignancies
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Hematology"
DOI: 10.1007/s12185-017-2300-7
Abstract: In mammalian cells, the DNA damage response (DDR) prevents the replication and propagation of DNA errors to the next generation, thus maintaining genomic stability. At the heart of the DDR are the related signaling kinases… read more here.
Keywords: dna damage; ddr; damage response; dna ... See more keywords
Impact of DNA damage repair defects on response to radium-223 and overall survival in metastatic castration-resistant prostate cancer.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of cancer"
DOI: 10.1016/j.ejca.2020.05.001
Abstract: PURPOSE Radium-223 is a targeted alpha radiation therapy for metastatic castration-resistant prostate cancer. DNA damage repair (DDR) defective prostate cancers, specifically genetic aberrations leading to homologous recombination deficiency (HRD), accumulate irreparable DNA damage following genotoxic… read more here.
Keywords: prostate; dna damage; radium; radium 223 ... See more keywords
Memory effect in DDR zeolite powder and membrane synthesis
Sign Up to like & getrecommendations! Published in 2019 at "Microporous and Mesoporous Materials"
DOI: 10.1016/j.micromeso.2018.12.031
Abstract: Abstract In this work, syntheses of crystalline DDR powder and DDR membranes were studied with regard to memory effects happening to the repetitively used synthesis vessel. It was found that promoted nucleation and growth towards… read more here.
Keywords: synthesis; memory; membrane; powder ... See more keywords
Adsorption of CO2 on high silica MFI and DDR zeolites: Structural defects and differences between adsorbent samples
Sign Up to like & getrecommendations! Published in 2020 at "Microporous and Mesoporous Materials"
DOI: 10.1016/j.micromeso.2019.109818
Abstract: Abstract Equilibrium isotherms have been measured for adsorption of CO2 on several different samples of high silica zeolites (silicalite, the aluminum free form of ZSM-5 and DDR, the aluminum free form of ZSM-58), prepared by… read more here.
Keywords: adsorption; adsorption co2; high silica; structural defects ... See more keywords
Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer
Sign Up to like & getrecommendations! Published in 2024 at "Leukemia"
DOI: 10.1038/s41375-024-02253-3
Abstract: Clonal hematopoiesis (CH) driven by mutations in the DNA damage response (DDR) pathway is frequent in patients with cancer and is associated with a higher risk of therapy-related myeloid neoplasms (t-MNs). Here, we analyzed 423… read more here.
Keywords: treatment; clonal hematopoiesis; ddr; ovarian cancer ... See more keywords
Ubiquitin-like proteins in the DNA damage response: the next generation.
Sign Up to like & getrecommendations! Published in 2020 at "Essays in biochemistry"
DOI: 10.1042/ebc20190095
Abstract: DNA suffers constant insult from a variety of endogenous and exogenous sources. To deal with the arising lesions, cells have evolved complex and coordinated pathways, collectively termed the DNA damage response (DDR). Importantly, an improper… read more here.
Keywords: like proteins; damage; damage response; ubiquitin like ... See more keywords
Edge-Terminated GaN Reverse Double-Drift IMPATT Structure for Efficient Millimeter-Wave Radiation
Sign Up to like & getrecommendations! Published in 2025 at "IETE Journal of Research"
DOI: 10.1080/03772063.2025.2477738
Abstract: An edge-terminated double-drift region (DDR) impact avalanche transit time (IMPATT) structure has been proposed for the efficient generation of millimeter-waves (mm-waves). A combination of mesa etching and nitrogen ion implantation techniques has been prescribed in… read more here.
Keywords: impatt structure; ddr; reverse; edge terminated ... See more keywords
Armed and disarmed in Eritrea: the regional dimension of DDR in post-2018 Ethiopia
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Eastern African Studies"
DOI: 10.1080/17531055.2024.2337496
Abstract: ABSTRACT In 2018, armed groups opposing the incumbent in Ethiopia, agreed to desert the violent means and participate in Disarmament, Demobilization and Reintegration (DDR). Like many DDR processes, it faced discrepant combatant data, lack of… read more here.
Keywords: armed groups; ddr post; regional dimension; 2018 ethiopia ... See more keywords
DDR: efficient computational method to predict drug–target interactions using graph mining and machine learning approaches
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx731
Abstract: Abstract Motivation Finding computationally drug–target interactions (DTIs) is a convenient strategy to identify new DTIs at low cost with reasonable accuracy. However, the current DTI prediction methods suffer the high false positive prediction rate. Results… read more here.
Keywords: method; graph; drug target; target interactions ... See more keywords