DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1‐Mediated NRF2 Ubiquitination
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DOI: 10.1002/advs.202204438
Abstract: Chemoresistance is the main obstacle in osteosarcoma (OS) treatment; however, the underlying mechanism remains unclear. In this study, it is discovered that DDRGK domain‐containing protein 1 (DDRGK1) plays a fundamental role in chemoresistance induced in… read more here.
Keywords: ddrgk1; ddrgk1 knockout; keap1; enhances osteosarcoma ... See more keywords