Articles with "ddx11" as a keyword



Dead/H-Box Helicase 11 (DDX11) Mutations Correlate with Increased Relapse Risk in Persons with Acute Myeloid Leukaemia and Promote Proliferation and Survival of Human AML Cells in Vitro and in Immune Deficient Mice

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Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-127831

Abstract: Background About one-half of persons with acute myeloid leukemia have normal cytogenetics but have diverse outcomes which might be explained, at least in part, by specific mutations. We focused on DDX11, the budding yeast ortholog… read more here.

Keywords: human aml; deficient mice; ddx11; immune deficient ... See more keywords