A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation
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DOI: 10.1093/nar/gkab180
Abstract: Abstract The lysine specific demethylase 1 (LSD1) plays a pivotal role in cellular differentiation by regulating the expression of key developmental genes in concert with different coregulatory proteins. This process is impaired in different cancer… read more here.
Keywords: novel transcriptional; ddx19a; regulatory cascade; coregulator ... See more keywords