DEAD-box RNA helicase 21 negatively regulates cytosolic RNA-mediated innate immune signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.956794
Abstract: DEAD-box RNA helicase 21 (DDX21), also known as RHII/Gu, is an ATP-dependent RNA helicase. In addition to playing a vital role in regulating cellular RNA splicing, transcription, and translation, accumulated evidence has suggested that DDX21… read more here.
Keywords: ddx21; rna helicase; rna; ifn production ... See more keywords
Pan-cancer analysis reveals DDX21 as a potential biomarker for the prognosis of multiple tumor types
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.947054
Abstract: Background DExD-box helicase 21 (DDX21) is an essential member of the RNA helicase family. DDX21 is involved in the carcinogenesis of various malignancies, but there has been no comprehensive research on its involvement in different… read more here.
Keywords: analysis; ddx21; gene; cancer ... See more keywords
DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication
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DOI: 10.3390/v13091765
Abstract: In cells, the contributions of DEAD-box helicases (DDXs), without which cellular life is impossible, are of utmost importance. The extremely diverse roles of the nucleolar helicase DDX21, ranging from fundamental cellular processes such as cell… read more here.
Keywords: ires dependent; fmdv ires; dependent translation; ddx21 ... See more keywords
DDX21 Interacts with WDR5 to Promote Colorectal Cancer Cell Proliferation by Activating CDK1 Expression
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DOI: 10.7150/jca.69216
Abstract: DEAD-box RNA helicase 21 (DDX21), is a nucleolar protein harboring ATP-dependent double-stranded RNA unwinding activities, essential in rRNA processing and ribosome biogenesis. However, its role in colorectal cancer (CRC) progression remains unclear. In this study,… read more here.
Keywords: cell; cell proliferation; expression; ddx21 ... See more keywords