Articles with "ddx39b" as a keyword



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DDX39B promotes translation through regulation of pre-ribosomal RNA levels

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Published in 2018 at "RNA Biology"

DOI: 10.1080/15476286.2018.1517011

Abstract: ABSTRACT DDX39B, a DExD RNA helicase, is known to be involved in various cellular processes such as mRNA export, splicing and translation. Previous studies showed that the overexpression of DDX39B promotes the global translation but… read more here.

Keywords: ribosomal rna; ddx39b; pre ribosomal; ddx39b promotes ... See more keywords
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DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy

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Published in 2020 at "BMC Biology"

DOI: 10.1186/s12915-020-0764-z

Abstract: Background Nuclear factor-κB (NF-κB) plays a prominent role in promoting inflammation and resistance to DNA damaging therapy. We searched for proteins that modulate the NF-κB response as a prerequisite to identifying novel factors that affect… read more here.

Keywords: pattern recognition; recognition receptor; alkylating chemotherapy; ddx39b ... See more keywords