DDX3X Deficiency attenuates Pyroptosis Induced by Oxygen-Glucose Deprivation/Reoxygenation in N2a Cells.
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DOI: 10.2174/1567202620666230522155944
Abstract: BACKGROUND NOD‑like receptor protein 3 (NLRP3) inflammasome-mediated pyroptosis is strongly related to cerebral ischemia/reperfusion (I/R) injury. DDX3X, the DEAD-box family's ATPase/RNA helicase, promotes NLRP3 inflammasome activation. However, whether DDX3X deficiency attenuates NLRP3 inflammasome-mediated pyroptosis induced… read more here.
Keywords: pyroptosis; nlrp3 inflammasome; n2a cells; ddx3x deficiency ... See more keywords