High-Throughput Screening Identifies Ascorbyl Palmitate As a SIRT2 Deacetylase and Defatty-Acylase Inhibitor.
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DOI: 10.1002/cmdc.202100343
Abstract: Small molecule inhibitors of SIRT2 are being developed because of their therapeutic potential in a variety of diseases. Here, we developed a high-throughput screen to identify novel SIRT2 inhibitors using a fluorescent SIRT2 probe, 1-aminoanthracene… read more here.
Keywords: defatty acylase; ascorbyl palmitate; deacetylase defatty; sirt2 ... See more keywords