Articles with "deacetylases complex" as a keyword



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Targeting Class I Histone Deacetylases in a "Complex" Environment.

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Published in 2017 at "Trends in pharmacological sciences"

DOI: 10.1016/j.tips.2016.12.006

Abstract: Histone deacetylase (HDAC) inhibitors are proven anticancer therapeutics and have potential in the treatment of many other diseases including HIV infection, Alzheimer's disease, and Friedreich's ataxia. A problem with the currently available HDAC inhibitors is… read more here.

Keywords: deacetylases complex; class histone; complex environment; histone deacetylases ... See more keywords