Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer.
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DOI: 10.1016/j.cbpa.2019.03.002
Abstract: The polypharmacology strategy of multi-targeting drugs acting on different biological pathways is capturing the researchers' attention, particularly in cancer. The simultaneous inhibition of two or more targets by drug combination or by a single 'hybrid… read more here.
Keywords: histone deacetylases; cancer; deacetylases epigenetic; epigenetic pillar ... See more keywords